Hepatic cryosurgery for recurrent hepatocellular
carcinoma after hepatectomy: a preliminary report.
Lam CM, Yuen WK, Fan ST.
Department of Surgery, University of Hong Kong, Queen Mary Hospital,
BACKGROUND AND OBJECTIVES: The treatment of choice
for recurrent hepatocellular carcinoma (HCC) is repeated resection.
However, only a small percentage of patients are suitable for further
hepatic resection. The aim of this study was to evaluate the surgical
risk and operative outcome of hepatic cryosurgery in patients with
recurrent HCC. METHODS: A retrospective analysis of patients with
recurrent HCC after previous curative hepatectomy treated with cryosurgery.
Four patients with recurrent HCC not suitable for further resection
were enrolled for cryosurgery, their clinical parameters, the operative
details and outcome were studied. RESULTS: No intraoperative or
postoperative complications were noted. The duration of operation
ranged from 3-5.2 hr and the operative blood loss from 173-1,300
ml. All patients are still alive with survival after cryosurgery
ranging from 12-23 mo (25-63 mo after the hepatic resection). Three
patients showed evidence of recurrent disease and one patient was
disease free. CONCLUSIONS: Hepatic cryosurgery is a safe therapy
for patients with unresectable recurrent HCC.
PMID: 9624039 [PubMed - indexed for MEDLINE]