[Article in German]
Romodanov AP, Sosulja JA, Laponogov OA,
In 35 patients with deep-lying and medial gliomas
(25 cases of glioblastoma multiforma, 10 cases of dedifferentiated
astrocytoma), stereotactic cryodestructions were performed after
preceding biopsies. Diagnosis was made in the usual manner, mainly
by means of angiography. Sites of action were the tumour mass proper
and the blood supply zones. In some cases, partial removal of the
tumour was carried out in the usual way before or after cryodestruction.
There are 3 kinds of further development after cryodestruction:
regression, slow progression and rapid progression. Progression
was found in 14 patients; 9 patients died within 2 weeks after the
operation. In their cases, cryodestruction was by far insufficient.
Dedifferentiated astrocytomas showed more a regressive behaviour
than multiform glioblastomas. The possibility of local chemotherapy
was also utilised.
PMID: 204132 [PubMed - indexed for MEDLINE]